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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
13.64
Human Site:
S809
Identified Species:
30
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
S809
I
L
I
S
I
K
S
S
D
S
D
E
S
Y
G
Chimpanzee
Pan troglodytes
XP_526066
929
104074
E568
A
L
R
L
E
A
T
E
T
Q
L
P
I
Y
T
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
M828
L
L
L
T
V
K
S
M
D
G
Y
E
S
Y
G
Dog
Lupus familis
XP_542327
1264
138869
M834
L
L
L
T
V
K
S
M
D
G
Y
E
S
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
S812
I
L
I
S
I
K
S
S
D
S
D
E
S
Y
G
Rat
Rattus norvegicus
P97573
1190
133575
S811
I
L
I
S
I
K
S
S
D
S
D
E
S
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
G658
D
G
K
T
A
P
G
G
E
K
A
Q
G
K
P
Chicken
Gallus gallus
XP_422567
1182
133482
S808
I
L
I
S
I
K
S
S
D
S
D
E
S
Y
G
Frog
Xenopus laevis
Q6P4S2
1019
115278
I658
T
K
Q
K
A
T
G
I
K
Y
N
L
P
S
W
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
L812
L
L
L
T
V
K
S
L
D
G
Y
E
S
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
E814
I
L
V
A
I
K
S
E
D
S
D
E
S
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
13.3
53.3
53.3
N.A.
100
100
N.A.
0
100
0
53.3
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
20
80
80
N.A.
100
100
N.A.
20
100
6.6
80
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
19
10
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
73
0
46
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
19
10
0
0
73
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
19
10
0
28
0
0
10
0
73
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
46
0
37
0
46
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
0
10
10
10
0
73
0
0
10
10
0
0
0
10
0
% K
% Leu:
28
82
28
10
0
0
0
10
0
0
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
10
10
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
37
0
0
73
37
0
46
0
0
73
10
0
% S
% Thr:
10
0
0
37
0
10
10
0
10
0
0
0
0
0
10
% T
% Val:
0
0
10
0
28
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
28
0
0
82
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _